It's not the absence of meaning, but rather the infinite regression of meaning that we should be worried about.
You see, every time you try to define meaning, it slips further into the abyss of ambiguity.
A paradox within a paradox, within another paradox, ad infinitum...Welcome to the never-ending cycle of self-referential absurdity.
But don't worry, it's not like we're trapped, or anything...Unless, of course, we're talking about the meaning of the box.